In which type of dementia do patients typically experience a decline in executive functioning?

Pick's Disease, also known as frontotemporal dementia, primarily affects the frontal and temporal lobes of the brain, leading to significant changes in personality, behavior, and executive functioning. Patients with this type of dementia often show marked impairments in their ability to plan, organize, and make decisions due to the degeneration of areas involved in these cognitive processes.

Executive functioning encompasses skills like problem-solving, abstract thinking, and the ability to manage time and space effectively. In Pick's Disease, these functions degrade as the disease progresses, which can manifest as inappropriate social behavior, a lack of insight, or decreased motivation. It is distinct from other forms of dementia, which may affect memory or language more prominently.

Other dementias such as Alzheimer's Disease and Vascular Dementia exhibit different cognitive profiles. While Alzheimer's primarily impacts memory initially, executive functioning may decline later in the disease. Similarly, Vascular Dementia often presents with mixed symptoms, including cognitive decline and memory problems, but it may not display the same degree of executive dysfunction as prominently as Pick's Disease. Therefore, the unique impact on executive functioning makes Pick's Disease the correct answer in this context.