What characterizes Huntington's Disease?

Huntington's Disease is characterized by a combination of motor dysfunction and cognitive decline. Uncontrolled movements, often referred to as chorea, are one of the hallmark symptoms of this neurodegenerative disorder. These movements can be erratic and can affect voluntary muscle control. Alongside these motor symptoms, individuals with Huntington's Disease commonly experience cognitive decline, which can lead to dementia over time. This combination of uncontrolled movements and cognitive impairment is a defining feature of the disease, making it clear why this answer is the correct option.

Other symptoms, such as mood swings or memory loss, may occur but are not as central to the diagnosis as the combination of motor and cognitive symptoms. This reinforces the multifaceted nature of Huntington's Disease, emphasizing both the motor and neurocognitive aspects as central to understanding and diagnosing the condition.